Listen ⚡️ DeSci Ep. #4 | Decentralizing Drug Development—with Paul Kohlhaas & Tyler Golato of Molecule
“Science as a practice is inherently meant to be decentralized. Science is meant to be open. Decentralized science is new in the context of how it's being described, but how I would define decentralized science as basically building the tools to help make open science more possible. And open science is something that has existed for decades.” — Tyler Golato
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ABOUT THIS EPISODE
Under the current centralized system, drug development happens in silos. Pharmaceutical companies don’t share information. Scientists run the same failed experiments over and over again. And the process of bringing a drug to market typically takes ten-plus years. But Paul Kohlhaas and Tyler Golato are building a new way to do drug development. A system that allows for collaboration and dramatically increases the speed of breakthroughs in healthcare.
CEO Paul and CSO Tyler are the Cofounders of Molecule, a decentralized biotech protocol that establishes a Web3 marketplace for research-related intellectual property.
On this episode of Boost VC, Paul and Tyler join us to explain how their personal experiences with the failures of healthcare inspired their interest in changing the system. They discuss Molecule's end-to-end ecosystem for bringing drugs to market, describing how their IP-NFT both protects innovation and makes it more open, sharable and collaborative.
Listen in for insight on Eroom's Law and learn how open science leads to enormous efficiency gains in the drug development process.
Topics Covered
How Paul & Tyler define science
Empirical discovery of knowledge
Progressive search for truth
What inspired Paul & Tyler’s interest in science
Personal experience with failures of healthcare
Potential for DeSci to foster new behaviors
Paul & Tyler’s failed experiment with crowdfunding
Tried to raise money for microdosing study
Partnership with University of Toronto
How Molecule has evolved since 2019
Ecosystem for bringing drugs to market
IP-NFT framework for collaboration
How to make scientists more open to sharing
Improve user experience
Streamline funding process
The power of Molecule’s IP-NFT framework
Intellectual property rights held on chain
Collectively owned by patients
The value prop for open science
Creates enormous efficiency gains
Makes drug development much cheaper
Jack Scannel’s naming of Eroom’s Law
Technology to discover drugs improving
Yet drug discovery output in decline
The goals for DeSci over the next decade
Extend quality of human health span
Make science self-sovereign, self-aware
How Paul & Tyler define success
Remain true to values and vision for life
Net positive impact on every person
Connect with Paul Kohlhaas & Tyler Golato
Molecule https://www.molecule.to/
Molecule on GitHub https://github.com/moleculeprotocol
Molecule on Discord https://discord.com/invite/uAGW7K4hQU
Molecule on YouTube https://www.youtube.com/channel/UCWYW5ho3L_d0EO_a619E7RQ
Molecule on LinkedIn https://www.linkedin.com/company/molecule-protocol
Molecule on Twitter https://twitter.com/molecule_dao
Paul on Twitter https://twitter.com/paulkhls
Tyler on Twitter https://twitter.com/GolatoTyler
Resources
Linum Labs https://www.linumlabs.com/
Molecule’s Crowdfunding Experiment with the University of Toronto https://www.molecule.to/blog/psychedelics-on-the-blockchain
NIH Grants and Funding https://www.nih.gov/grants-funding
Simon de la Rouviere on Bonding Curves https://www.youtube.com/watch?v=-k4M6QAW2pM
Jack Scannell on Eroom’s Law https://refoundable.com/research/life-after-erooms-law-interview-with-jack-scannell.html
Meme Lordz https://memelordz.io/
North American Association of Technology Transfer http://aim.autm.net/
Ray Kurzweil https://www.kurzweilai.net/
Peter Diamandis https://www.diamandis.com/
Abundance 360 https://www.abundance360.com/summit